Neutrophils: Non Viable

Appearance Non-viable neutrophils are: A healthy neutrophil is irregular, dynamic, and actively streaming — the opposite of the non-viable pattern. Meaning & Implications Non-viable neutrophils are one of the strongest indicators of immune suppression, linked…

Neutrophil Count Increased / Decreased

Appearance This post refers to the overall count, not morphology.Neutrophils make up 50–70% of all white blood cells.Changes in count are evaluated over several fields of view. Increased Neutrophils (Neutrophilia) Causes: A) Acute Bacterial Infection…

Neutrophils: Hypersegmentation

Appearance Hypersegmented neutrophils are neutrophils with: They appear “over-mature” or “stretched.” Meaning & Implications Hypersegmentation is a classic sign of impaired DNA synthesis, commonly due to: A) B12 or Folate Deficiency This is the primary…

Anisopoikilocytosis – RBC Anomaly Details

Appearance The majority of RBCs vary greatly in shape and size, displaying irregular edges, varying sizes, membrane projections and fragments. Some RBCs are rod-shaped or may resemble bowling pins. Target cells are usually also present.…

Cloud Patterns – RBC Anomaly Details

Appearance RBCs with indentations appearing similar to cloud drawings. These may appear as a ‘ridge’, affecting many RBCs over a large area in the sample or as single RBCs. Fibrin clusters may be observed surrounding…

Aggregation – RBC Anomaly Details

Appearance Large numbers of RBCs randomly piled on top of one another. Also referred to as clumping or ‘blood sludge’ as the cells are severely agglutinated. Erythrocyte aggregation can be distinguished from rouleau in that…

Spherocytes – RBC Anomaly Details

Appearance Spherocytes are small, spherical RBCs, approximately two-thirds the diameter of normal RBCs and lack a zone of central pallor. They appear significantly darker and smaller than normal RBCs in brightfield and have a thicker…

Target Cells – RBC Anomaly Details

Appearance The term “target cell” arises from the cell’s resemblance to a target. Also referred to as codocytes and anulocytes, these cells range from hypochromic cells, where the central area of pallor is much larger…

Rouleau – RBC Anomaly Details

Appearance Rouleau is French for ‘rolls’. The term describes the appearance of red blood cells (RBCs) in this condition, forming strings of overlapping RBCs stacked on top of one another. Relevance At the periphery of…

Understanding Your Live Blood Observation

What This Session Is — and What It Is Not A live blood observation offers a real-time view of how your blood is behaving in its current environment. We look at: This provides a snapshot…